Next generation sequencing was a massive breakthrough for reading DNA. We’ve applied those same principles to synthesis, giving researchers a game changing way to write genetic material.
Terminal Deoxynucleotidyl Transferase (TdT) has been engineered to be the engine of our template free synthesis system, delivering fast synthesis with low error rates.
Novel 3’ reversibly terminated nucleotides are employed to control oligo elongation to a single base addition per cycle leaving scar-free, natural DNA.
Biocompatible resins are employed as the solid support for synthesis to produce oligos at a scale necessary for most of today’s molecular biology applications.
Upon completion of synthesis, oligos are liberated from the solid support and are purified to remove any contaminants that could inhibit downstream use.
Oligos are delivered, in plates, ready-to-use, having been quantified and normalized by the system.