Careers

We are synthesizing a technology revolution. Join us.
General & Administration

The Role

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

We are looking for an experienced Finance Program Manager for a variety of projects within DNA Script’s rapidly growing and cutting-edge product portfolio. The Program Manager will develop budgets/timelines for projects, manage resources, and as well as drive development projects varying in size and complexity. The PM will interface with internal and external partners to achieve project goals, milestones, and timelines. The ideal candidate must be a skilled professional with strong negotiation and influencing skills, with the ability to work independently, handle multiple tasks in parallel, and communicate effectively with all levels of the organization.

Responsibilities

  • Provide management and leadership skills to drive execution on project goals for a portfolio of projects.
  • Collaborate cross-functionally to create, execute and communicate overall project plans (scope, schedule, staffing plans, quality, risk management, budget, and procurement) and revise them appropriately to meet changing project needs and requirements.
  • Identify needs for changes to plan and communicate them to the team and stakeholders to ensure program goals are in alignment with business objectives.
  • Introduce, champion, and educate stakeholders (company-wide) on phase (or stage-gate) methodologies and drive best practices.
  • Organize and lead routine phase (or stage- gate) reviews with an executive approval committee.
  • Identify and resolve or escalate program issues, facilitate tradeoff decisions, and remove obstacles.
  • Ensure product development efforts adhere to internal processes and design control standards.
  • Continuously analyze and manage risks to enable successful project completion.
  • Define and optimize project management and development processes, methodologies, and tools to improve organizational efficiency and effectiveness.
  • Apply best practices and knowledge of internal/external business challenges to improve products.
  • Manage cross-functional resources, project timelines and project budgets required to successfully drive projects and initiatives.

Experience

  • Have a passion for process improvements and innovative solutions.
  • Bachelor’s degree
  • At least 5 years of demonstrated experience leading multiple complex programs from design to delivery.
  • A proven track record of effectively interacting with C-Suite executives
  • Strong interpersonal and facilitation skills with a proven ability to effectively build relationships and achieve consensus across a wide range of functions and constituents despite natural tensions between those functions (e.g. Finance and Commercial)
  • Demonstrated ability to lead and achieve results by influence alone.
  • Strong quantitative and qualitative skills; detail-oriented with ability to see the big picture and to work effectively at both high and detailed levels.
  •  Outstanding written and oral communication skills

Miscellaneous

  • Job location: South San Francisco
  • Start date: Q1 2021
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a Legal Counsel who will be primarily responsible for advising the management on all legal and contractual aspects related strategic matters as well as current operations.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a product portfolio and technology that will have far-reaching impact across biological sciences.    

The position will be Paris, France based but will also involve covering remotely US activities.

Responsibilities

  • Assessing legal risks and advising executive, senior management and board on various matters such as legal and contractual rights (including labor law, partnerships, international ventures, corporate finance, equity structure etc.), and new and existing laws.
  • Leading or supporting discussions with legal authorities (tax administration, work inspection, construction permits etc.)
  • Managing organization’s legal matters.
  • Examining and creating draft agreements, such as employment, partnerships and vendor or sales agreements.
  • Maintaining knowledge of organization’s operations and legal documents.
  • Conducting legal research and reviewing company’s litigation strategy pertaining to legal actions.
  • Promulgating and creating directives of corporate acts and decisions.
  • Preserving all corporate records.
  • Handling statutory filings, such as licensing forms.
  • Liaising with outside counsel regarding their assignments.
  • Creating new entities and managing organization’s intellectual property.

Experience

  • Proven experience as a Legal Counsel in business environment with at least 5 years of professional experience
  • Excellent knowledge and understanding of corporate law and procedures in France and in the US
  • Full understanding of the constraints of a corporation
  • Demonstrated ability to create defensive or proactive legal strategies
  • High degree of professional ethics and integrity
  • Sound judgement and ability to analyze situations and information
  • Outstanding communication skills
  • Master degree in Law or J.D. degree
  • MA or BSc in Business Administration will be considered an advantage

Miscellaneous

  • Job located in Le Kremlin-Bicêtre (Paris area)
  • Start date: ASAP
  • Contact: jd@dnascript.co
Apply now

The Role

We are looking for an experienced Product Development Program Manager for a variety of projects within DNA Script’s rapidly growing and cutting-edge product portfolio. The Program Manager will develop budgets/timelines for projects, manage resources, and as well as drive development projects varying in size and complexity from Concept through Commercialization. The PM will interface with internal and external partners to achieve project goals, milestones, and timelines. The ideal candidate must be a skilled team leader with strong negotiation and influencing skills, with the ability to work independently, handle multiple tasks in parallel, and communicate effectively with all levels of the organization.

Responsibilities

  • Provide management and leadership skills to drive execution on project goals for a portfolio of projects.
  • Collaborate cross-functionally to create, execute and communicate overall project plans (scope, schedule, staffing plans, quality, risk management, budget, and procurement) and revise them appropriately to meet changing project needs and requirements.
  • Identify needs for changes to plan and communicate them to the team and stakeholders to ensure program goals are in alignment with business objectives.
  • Introduce, champion, and educate stakeholders (company-wide) on phase (or stage-gate) methodologies and drive best practices.
  • Organize and lead routine phase (or stage- gate) reviews with an executive approval committee.
  • Identify and resolve or escalate program issues, facilitate tradeoff decisions, and remove obstacles.
  • Ensure product development efforts adhere to internal processes and design control standards.
  • Continuously analyze and manage risks to enable successful project completion.
  • Define and optimize project management and development processes, methodologies, and tools to improve organizational efficiency and effectiveness.
  • Apply best practices and knowledge of internal/external business challenges to improve products.
  • Manage cross-functional resources, project timelines and project budgets required to successfully drive projects and initiatives.

Requirements

  • Have a passion for commercializing platforms that are at the leading-edge innovation in life science.
  • Bachelor’s degree and or post graduate degree in Life Sciences, Engineering, or related field.
  • At least 5 years of demonstrated experience leading multiple complex programs from design to delivery.
  • Formal PMP certificate from an accredited program.
  • At least 5 years demonstrated experience in product development.
  • Sound grasps of the key business drivers and considerations in the biotech, pharmaceutical, medical device and /or life science industries.
  • Strong interpersonal and facilitation skills with a proven ability to effectively build relationships and achieve consensus across a wide range of functions and constituents despite natural tensions between those functions (e.g. Marketing vs. RnD).
  • Demonstrated ability to lead and achieve results by influence alone.
  • Strong quantitative and qualitative skills; detail-oriented with ability to see the big picture and to work effectively at both high and detailed levels.
  • Ability to travel up to 25% domestic and internationally.

Preferably

  • Start-up mind-set is strongly preferred; demonstrated by participation in one
  • Experience managing a life science system program involving a hardware and software platform as well as reagent kits
  • Understanding of the new product introduction and product lifecycle management processes.

Miscellaneous

  • Job location: South San Francisco, US or Paris, France.
  • Requires travel among DNA Script corporate offices and client sites throughout US and Europe.
  • Start date: Q1 2021
  • Contact: hiring@dnascript.co
Apply now

The Role

We are seeking a Sales Executive in the West coast of US for a field sales-based position responsible for the territory sales plan. The Territory Account Manager will have strong technical knowledge in Molecular biology applications and will demonstrate technical credibility to effectively consult with customers to influence key decisions on technology and product choices. Strong business acumen is required to build successful account and territory plans and translate territory strategy into business results. The ideal candidate will have a strong history of account relationships with key thought leaders in the Next Gen Sequencing, PCR, qPCR and Sanger Sequencing space.

Responsibilities

  • Demonstrates technical credibility to consult with customers on technology solutions.
  • Demonstrates funnel management skills with strong hunting/prospecting and closing skills.
  • Commitment to rigorous territory planning, market knowledge, both accurate and timely forecasting.
  • Develops and manages to a business plan to meet or exceed business goals for the territory.
  • Understands scientific project needs and business needs of the customer to win the business.
  • Consistently and accurately manages sales process including sales forecasting, pipeline management, and sales tracking using the CRM system and other designated IT tools.
  • Develops and maintains current knowledge of genetic analysis markets, products, and buying practices required to effectively compete in the assigned territory.
  • Utilizes product and application knowledge across the genetic analysis portfolio to successfully conduct selling presentations.
  • Assists in the identification and recruitment of new salespeople as required.
  • Ensure that customers are fully satisfied.
  • Represent the company professionally, ethically, and morally at all times.

Requirements

  • Start-up mind-set.
  • Bachelor’s degree in Biology, Molecular Biology, Biochemistry, or related field; or the equivalent knowledge and experience.
  • Minimum of 3-5 years sales experience in Life Science, with capital equipment experience.
  • Strong desire to win business and establish long term customer relationships.
  • Extensive knowledge of Molecular biology techniques.
  • Ability to travel as needed to be successful in this field-based role.

Nice to have skills & background:

  • A Master’s or PhD degree is desirable.
  • Key account management experience a plus

Miscellaneous

  • Job location: West Coast US, preference in San Francisco bay area
  • Requires travel among DNA Script corporate offices and client sites throughout Western US
  • Start date: Q2 2021
  • Contact: kfe@dnascript.co
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionately impatient people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write.” We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our DNA On Demand platform not only has the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.    

The Role

We are looking for an experienced Marketing Communications Manager who can be our messaging “conductor” and develop communications from ground zero. You will own the development of the strategic messaging and direct the tactical integration of our brand and product messaging in communications across all media necessary to achieve our sales objectives. You will drive the communications roadmap, with a strong focus on digital marketing, that maximizes the reach of our products & services and delivers on our growth expectations. This is a mission critical role on the Commercial team that requires collaboration with team members in Marketing, Sales, Product Development and senior management. We’re looking for the leader who can bring together the essential elements of our brand in all of our product focused and corporate communications.  You will be the visionary, drive the tempo and harmonize our communications to deliver success.

Responsibilities

  • Direct and execute corporate and product marketing communications acting as brand champion; own messaging across all media channels.
  • Own corporate and product messaging, gain buy-in across leadership, and deploy consistently across channels. Periodically review and modify to address applicable market audiences.
  • Lead and develop go-to-market plans for new product introductions by ensuring consistent      messaging and positioning, and coordinate execution across communication media channels and      sales training     .
  • Drive & execute product marketing programs and campaigns to accelerate adoption of our platforms through strong partnerships with product management, applications, and sales.
  • Develop, budget, monitor, and evaluate the success of campaigns for optimization and continued effectiveness; determine ROI.
  • Formulate and drive digital strategy and content roadmap to transform and maximize reach, from ideation through execution and implementation.
  • Proactively identify, execute, and refresh content strategies to generate awareness, demand, and improved customer experience and conversion.
  • Own and manage digital marketing assets; build a collateral portfolio for digital, virtual & print interactions.
  • Collaborate with Product Management and Applications to develop and produce awareness & education materials for market outreach & expansion.
  • Direct and manage consultants, freelancers, agencies in multiple countries.
  • Develop product packaging in line with brand.
  • Direct PR/IR programs to establish company as leader to attract investors, customers, and employees.
  • Own marketing campaign management and data capture within the CRM system.

Requirements

  • Have a passion for commercializing platforms that are game-changing and require an audience behavioral shift
  • Proven experience in building communications and assets across marketing channels/media from ground zero
  • Experienced with investor communications; IPO experience a plus
  • Experienced in global product launches or specific programs and campaigns to support corporate & commercial strategy
  • Have the drive and initiative to learn new skills and can demonstrate complete ownership of assigned marketing campaigns and programs
  • Creative thinker and can help establish new frontiers in how we communicate with prospects, customers, investors, be unafraid to re-draw the box, etc.
  • Ability to convert complex technical concepts and product capabilities into crisp messages on benefits for the target audience
  • Effectiveness in building relationships with key stakeholders necessary for collaboration at all levels and influence without authority. Gain alignment and achieve results by power of influence alone
  • BA/BS degree in marketing or equivalent, preferably with background in Biological Sciences
  • 10+ years of marketing experience in a similar position within the life science industry.
  • Strong writing & graphic design appreciation skills are required for this role; must demonstrate proven experience in writing digital content, technical writing, and copywriting as well as knowing when the right picture or graphic will speak more effectively. .
  • Excellent communication skills with ability to present technical presentation in sales trainings, small groups and customers.
  • Ability to travel up to 25% domestic and international.

Preferably

  • Start-up mind-set and experience  is strongly preferred.
  • Experienced across the marketing continuum
  • Understanding of the new product introduction and product lifecycle management processes
  • Account, vendor, or project management experience

Miscellaneous

  • Job location: South San Francisco, US or Paris, France
  • Requires travel among DNA Script corporate offices and client sites throughout US and Europe.
  • Start date: Q1 2021

Contact: hiring@dnascript.co

Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionately impatient people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write.” We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our DNA On Demand platform not only has the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.    

The Role

We are looking for an experienced Marketing Communications Manager who can be our messaging “conductor” and develop communications from ground zero. You will own the development of the strategic messaging and direct the tactical integration of our brand and product messaging in communications across all media necessary to achieve our sales objectives. You will drive the communications roadmap, with a strong focus on digital marketing, that maximizes the reach of our products & services and delivers on our growth expectations. This is a mission critical role on the Commercial team that requires collaboration with team members in Marketing, Sales, Product Development and senior management. We’re looking for the leader who can bring together the essential elements of our brand in all of our product focused and corporate communications.  You will be the visionary, drive the tempo and harmonize our communications to deliver success.

Responsibilities

  • Direct and execute corporate and product marketing communications acting as brand champion; own messaging across all media channels.
  • Own corporate and product messaging, gain buy-in across leadership, and deploy consistently across channels. Periodically review and modify to address applicable market audiences.
  • Lead and develop go-to-market plans for new product introductions by ensuring consistent      messaging and positioning, and coordinate execution across communication media channels and      sales training     .
  • Drive & execute product marketing programs and campaigns to accelerate adoption of our platforms through strong partnerships with product management, applications, and sales.
  • Develop, budget, monitor, and evaluate the success of campaigns for optimization and continued effectiveness; determine ROI.
  • Formulate and drive digital strategy and content roadmap to transform and maximize reach, from ideation through execution and implementation.
  • Proactively identify, execute, and refresh content strategies to generate awareness, demand, and improved customer experience and conversion.
  • Own and manage digital marketing assets; build a collateral portfolio for digital, virtual & print interactions.
  • Collaborate with Product Management and Applications to develop and produce awareness & education materials for market outreach & expansion.
  • Direct and manage consultants, freelancers, agencies in multiple countries.
  • Develop product packaging in line with brand.
  • Direct PR/IR programs to establish company as leader to attract investors, customers, and employees.
  • Own marketing campaign management and data capture within the CRM system.

Requirements

  • Have a passion for commercializing platforms that are game-changing and require an audience behavioral shift
  • Proven experience in building communications and assets across marketing channels/media from ground zero
  • Experienced with investor communications; IPO experience a plus
  • Experienced in global product launches or specific programs and campaigns to support corporate & commercial strategy
  • Have the drive and initiative to learn new skills and can demonstrate complete ownership of assigned marketing campaigns and programs
  • Creative thinker and can help establish new frontiers in how we communicate with prospects, customers, investors, be unafraid to re-draw the box, etc.
  • Ability to convert complex technical concepts and product capabilities into crisp messages on benefits for the target audience
  • Effectiveness in building relationships with key stakeholders necessary for collaboration at all levels and influence without authority. Gain alignment and achieve results by power of influence alone
  • BA/BS degree in marketing or equivalent, preferably with background in Biological Sciences
  • 10+ years of marketing experience in a similar position within the life science industry.
  • Strong writing & graphic design appreciation skills are required for this role; must demonstrate proven experience in writing digital content, technical writing, and copywriting as well as knowing when the right picture or graphic will speak more effectively. .
  • Excellent communication skills with ability to present technical presentation in sales trainings, small groups and customers.
  • Ability to travel up to 25% domestic and international.

Preferably

  • Start-up mind-set and experience  is strongly preferred.
  • Experienced across the marketing continuum
  • Understanding of the new product introduction and product lifecycle management processes
  • Account, vendor, or project management experience

Miscellaneous

  • Job location: South San Francisco, US or Paris, France
  • Requires travel among DNA Script corporate offices and client sites throughout US and Europe.
  • Start date: Q1 2021

Contact: hiring@dnascript.co

Apply now
Product Development

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a motivated and efficient Verification Engineer who will be focused on enabling and testing our DNA synthesis technology and the development of DNA Script’s commercial product. This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.    

The position will be US based, in the South San Francisco, California office.

Responsibilities

  • Lead the definition, design, and execution of system verification activities on instrument projects
  • Determine strategy for testing product and sub-system requirements, including how requirements will be tested, sample size, resource and material needs
  • Develop and write system verification test methods to evaluate product requirements
  • Writing and executing test verification and validation protocols and associated summary reports and other related documents
  • Conduct representative DNA synthesis experiments to augment user-oriented testing
  • Contribute to system qualification executions, FAT and QC Release procedures for pre-production test units
  • Assist in development of specifications as they relate to the system and intended use.
  • Exercise independent judgment and apply solution thinking, problem solving, and troubleshooting
  • Use manufacturing, test, development, and/or diagnostic equipment, including, but not limited to, test programs, oscilloscopes, signal generators and specialized test apparatus.
  • Work closely with development engineers to conduct engineering tests, collect performance data, and/or assist in research work.
  • Maintain a clean work environment including instruments and equipment and workspace

Experience

  • Bachelor’s degree in engineering discipline or molecular biology-related scientific discipline
  • 2-5 years of verification and validation experience in a regulated industry; in vitro diagnostics, medical device, or biotech preferred
  • Experience in systems verification and validation principles or studies while working in biotech, pharma industry, clinical research, or other relevant industry.
  • Experience in product development and design control.

Ideal Candidate will have

  • Experience with Development and execution of test method validations, Installation and qualification of QC equipment systems, and Computer Systems Validation
  • Attention to detail and ability to identify and remediation issues found during testing.
  • Highly effective verbal and written skills, including technical authorship.
  • Ability to meet technical objectives and solve challenges under conditions of ambiguity and rapid change.
  • Excellent listening, written, and oral communication skills.
  • Experience running and trouble-shooting complex instruments including electromechanical systems, especially linear actuators and fluidics.
  • Extensive experience diagnosing and correcting problems with instruments or equipment.
  • Experience and aptitude with testing light mechanical systems. Experience working on analytical instruments combining mechanisms, electronics, automation, and fluidics.
  • Experience in reliability or life testing. Experience developing fixtures and instrumentation for assembly and testing.

Miscellaneous

  • Job located in South San Francisco
  • Start date: Q2 2021
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

The Role   

DNA Script is actively searching for an accomplished Field Service Engineer to support our partners and customers in their use and application of DNA Script’s commercial product. 

The individual will be responsible for leading complex technical inquiries in the field including troubleshooting and repairs, coordinating customer feedback and interactions, and representing user experiences within the company to aid development of next generation products. 

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have a far-reaching impact across biological sciences.    

The position will be remote based in the San Francisco Bay area and within commuting distance of our South San Francisco, California office.

Responsibilities

  • Installs and optimizes hardware/software/network products and configurations at customer sites.
  • Diagnoses and resolves product performance problems.
  • Performs maintenance and repairs.
  • Documents all field activity performed and ensures timely escalation of difficult issues for quick resolution.
  • Ensures customer satisfaction by advising customers on preventive maintenance and configurations, which may impact product performance.
  • Proactively responds to potential equipment issues to prevent unplanned interruption of customers’ business.
  • Delivers fully integrated solutions, which may include peripherals, communications, operating systems and applications software.
  • Train other field engineers and customers in the company’s system products. 
  • Serve as the primary point of contact for support within the western United States region ensuring all inquiries and complaints are documented, and customers are kept informed of issue resolution. May occasionally be required to provide support in other geographic areas.
  • Provide user-oriented and service-related  input to ongoing and new development projects.
  • Provides support of instrument operations and participates in product training within our South San Francisco  laboratory.
  • Represents DNA Script to customers and ensures customer satisfaction and high-quality service and support experiences. 
  • Ensures customer inquiries, complaints and outcome of service activities are documented in the company’s database.

Experience

  • Bachelors degree within the science field — e.g. biomedical engineering,  analytical biochemistry, biotechnology or similar is highly preferred
  • 4+ years of experience in a similar position and/or experience as an end-user of analytical instrumentation
  • Associates degree within the engineering field (electronics, mechanical) will be considered with 6+ years experience in a similar position working with qPCR instruments and liquid handling robotic systems.

Ideal Candidate will have

  • Experience or expertise with Laboratory Automation solutions (eg. pipetting robots, electronics and linear actuators) and systems involving reagents and consumables
  • Experience with troubleshooting and problem solving. Customer service and solutions-oriented, with capability to precisely document issues, root cause analyses, troubleshooting experimentation and resolutions/repairs.
  • Ability to effectively communicate with customers to ensure understanding of services and troubleshooting performed, as well as ensuring overall customer satisfaction with company products.
  • DNA Synthesis Experience, or Utilization of Synthetic Oligos in a biochemical application.
  • Excellent written and verbal communication skills.
  • Works well in a collaborative team environment but is also able to work independently.
  • Ability to collect technical data and produce high quality and professional presentation materials to communicate data and conclusions internally to stakeholders such as marketing and development teams to transfer knowledge about key field issues.
  • Ability to travel extensively including overnight travel as dictated by business needs

Miscellaneous

  • Remote job based on the West Coast of the USA. Requires up to 75% travel to corporate offices and client sites throughout Western region of the US and other parts of North America.
  • Start date: Q2 2021
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a motivated and efficient Engineering Technician who will be focused on enabling and testing our DNA synthesis technology and the development of DNA Script’s commercial product. This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.    

The position will be US based, in the South San Francisco, California office.

Responsibilities

  • Work closely with team members to improve quality and performance of mechatronic and automation platforms
  • Perform mechanical, electrical, and fluidic tests on prototypes.  Document results clearly, using approved templates
  • Operate, maintain, and perform advanced service on prototypes.  Address issues in a timely manner.
  • Troubleshoot, repair and requalify prototypes and associated test equipment .
  • Assemble components, subsystems, and systems for testing.
  • Perform operational test and fault isolation on systems and equipment.
  • Assist in determining methods or actions to remedy malfunctions.
  • Assist in the design, construction, test and check-out of test equipment.
  • Use manufacturing, test, development, and/or diagnostic equipment, including, but not limited to, test programs, oscilloscopes, signal generators and specialized test apparatus.
  • Work closely with development engineers to conduct engineering tests, collect performance data, and/or assist in research work.
  • Maintain a clean work environment including instruments and equipment and workspace

Experience

  • Bachelor’s degree in engineering discipline with 1 year of experience

Ideal Candidate will have

  • Experience with instruments including electromechanical systems, especially linear actuators and fluidics.
  • Extensive experience diagnosing and correcting problems with instruments or equipment.
  • Experience and aptitude with testing light mechanical systems.
  • Familiarity with electrical circuits and power supplies.
  • Ability to follow documented  procedures as well as keep organized lab notebook
  • Experience using mechanical tools to assemble and disassemble instrument components, modules, and full systems
  • Experience working on analytical instruments combining mechanisms, electronics, automation, and fluidics.
  • Hands-on experience with breadboard/prototype builds and automation/fluidics optimization.
  • Ability to troubleshoot electronic circuits.
  • Experience in reliability or life testing. Experience developing fixtures and instrumentation for assembly and testing.

Miscellaneous

  • Job located in South San Francisco
  • Start date: Q2 2021
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a Senior-Level Robotics and Automated Systems Architect to lead and manage the development and improvement of our DNA synthesis instrument control software.   This individual will be responsible for interfacing with and managing external and internal software development resources, reviewing and improving the instrument control software architecture, and leading efforts to improve and extend the capabilities of this software in current and future products. This individual will work closely with systems engineering to enable clear definition and organization of software requirements, design specifications and test cases, enabling performant and robust system operation.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.    

The position will be US based, in the South San Francisco, California office.

Responsibilities

  • Management of Software Development cycles across internal and external teams, and detailed synchronization of internal and external resources and projects. 
  • Facilitation of the integration of internal and external teams into a shared scrum team.
  • Serve as scrum master, grooming the backlog, setting the scope for each sprint, ensuring priority items are dealt with first, and on time release of new features and builds.
  • Prioritization of the team’s development time to create an effective balance between prototyping/experimentation and product related tasks (refactoring existing code, producing new features, creating tests).
  • Definition of acceptance criteria for features, required testing (software & integration), assessment of risk associated with new features, and ensuring that the software capabilities respond to the requirements
  • Definition of  content for releases, defining & maintaining release program, version numbers and deadlines.
  • Definition of  required tests to be passed before a release candidate is made an official release.
  • Coach and mentor developers, driving best practices in software development for complex systems requiring scheduled and coordinated activities
  • Refine and expand on existing software user needs and high level requirements, organize new software requirements under this framework
  • Update and maintain the Software Requirement/Specification (SRS) and translate any new or revised Product Requirements into Software Requirements.
  • Responsible for managing and communicating project definition, development milestones, project schedules, and project status in the development of new software releases 
  • Lead software projects based on strong understanding of system and software lifecycle – from feasibility definition and experimentation to verification and validation. We are looking for someone who is flexible and can respond to changes swiftly, energetically, and enthusiastically.
  • Manage the software project to schedule and ensure timely completion of deliverables
  • Collaborate closely and effectively with other internal and external teams to promote cross-team technology and knowledge sharing.
  • Interact with all technical disciplines, software and hardware engineering, scientific, product support, and additional external development teams.

Experience

  • Minimum B.S. degree or equivalent in Computer Science, Engineering, Biomedical Engineering discipline
  • 5+ years managing software projects involving control of hardware/robotics/fluidic systems
  • 5+ years developing software for laboratory automation, robotics or similar mechatronic systems.
  • Strong experience coding in C/C++.
  • Strong familiarity with project management software tools, methodologies, and best practices
  • Excellent organizational skills and an ability to keep others organized, including managing activities across global work forces
  • Experience seeing projects through the full life cycle, and an ability to pair a system-level view with day-to-day technical knowledge
  • Excellent analytical skills, attention to detail, and multi-tasking

Ideal Candidate will have

  • Foundational understanding of system software fundamentals and strong interest in improving process
  • Strong track record of on-time project delivery and managing entire project life cycle
  • Ability to influence teams to adopt best practices
  • Self-motivated and proactive with critical thinking and resourcefulness to drive the project to success, making an impact in health technologies
  • Experience in Biotechnology area is a significant plus

Miscellaneous

  • Job located in South San Francisco
  • Start date: Q2 2021

Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a Software Instrumentation Engineer to champion software development and software/system integration efforts for complex mechatronic systems.

The individual will lead internal software functional development along with contributing in all stages of product development from prototype integration and optimization through commercialization.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.    

The position will be US based, in the South San Francisco, California office.

Responsibilities:

  • Develop and integrate instrument control software from the prototype phase through release to manufacturing.
  • Develop connectivity solutions in an IoT style environment
  • Implementation of user interface instrument control into a web-based application
  • Improvement and refinement of instrument control user interface workflow and usability based on user feedback and to adhere to company branding and design guidelines
  • Develop software using C/C++ for use in life science laboratory automation and DNA Synthesis platforms and systems.
  • Participate in SW architecture development and risk mitigation activities, code reviews, system bring-up, integration, test, debug and verification activities
  • Work with other disciplines (EE, ME, SW) to define requirements, design, test, and debug embedded systems.
  • Interface with and collaborate with internal and external development partners, accelerating product development
  • Design, develop, test, deploy, maintain and improve software.
  • Manage individual project priorities, deadlines and deliverables.
  • Produce professional documentation and presentations.

Experience:

  • A Bachelor’s in Computer Science, Computer Engineering or relevant technical field.
  • 2-3 years of relevant work experience.
  • Development experience within embedded systems/firmware design for automation systems.
  • Strong experience coding in C/C++.
  • Strong experience developing test methods, test simulation and test automation using latest technologies.
  • Development experience using QT Creator or any other similar software package for application user interfaces
  • Experience in Biotechnology area is a significant plus
  • Experience in development of control software for laboratory automation systems is a significant plus

Ideal Candidate will have:

  • Knowledge of Unix/Linux environments and kernel development.
  • Knowledge of State Machines
  • Great with Python: In-depth knowledge of threading model, data structures, experience creating Python bindings in C and C++, and experience with regular expressions.
  • Use of source code management (SCM) tools (preferably GIT).
  • The highest level of personal honesty, integrity and commitment; unquestionably walks the talk so others want to follow.

Miscellaneous

  • Job located in Paris, France
  • Start date: As soon as possible.
  • Contact: cdm@dnascript.co
Apply now

The Role

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a Senior Back-end Software Engineer to implement the web-based Lab Information Management System.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences. 

Responsibilities

  • Design and develop e-commerce application supporting our business and product needs.
  • Work with product management and marketing to capture and define software requirements and influence overall product implementation direction.
  • Work closely with UX design personnel, clients and potential customers to understand their needs, objectives, and use cases, and develop applications meeting these specifications
  • Strong technical leadership skills with the ability to solve complex problems
  • Constant quality improvement of code and infrastructure

Qualifications and experience

Essential

  • A Bachelor’s Degree, or a Master’s Degree in software engineering or related field.
  • 5+ years of software development in an e-commerce environment using Java.
  • Prior experience developing and launching cloud-based production SaaS on AWS.
  • Experience developing server-based application and micro-services using Java frameworks like Spring Boot, Play, etc.
  • Experience developing against both SQL and No-SQL with strong database knowledge and design.
  • Experience with Atlassian applications including BitBucket, JIRA, Confluence, and other 3rd party development tools and utilities.
  • Self-motivated, self-starting, an attention to detail and a great team player.
  • The highest level of personal honesty, integrity and commitment; unquestionably walks the talk so others want to follow.
  • Strong communication skills.

Desirable

  • Familiarity with enterprise NGS cloud-based systems.
  • Experience integrating with Oracle’s ERP or NetSuite via web services API or equivalent.
  • Experience developing micro-services using Python with web service frameworks like Flask
  • Background in biological sciences, DNA applications, either from education or work experience.

Location

  • Job located in Paris, France
  • Start Date: ASAP
  • Contact: ftn@dnascript.co
Apply now

The Role

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a Senior Front-end Software Engineer to implement the web-based Lab Information Management System.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences. 

Responsibilities:

  • Design and develop e-commerce application supporting our business and product needs.
  • Work with product management and marketing to capture and define software requirements and influence overall product implementation direction.
  • Work closely with UX design personnel, clients and potential customers to understand their needs, objectives, and use cases, and develop applications meeting these specifications.
  • Strong technical leadership skills  with the ability to solve complex problems.
  • Constant quality improvement of code and infrastructure.

Requirements:

  • A Bachelor’s Degree, or a Master’s Degree in software engineering or related field.
  • 5+ years of software development in an e-commerce environment with various web-based applications, web store, inventory, order management, analytical reports, etc.
  • Prior experience developing and launching web-based SaaS on AWS and/or stand-alone software package.
  • Experience developing web applications using TypeScript, ReactJS, Apollo, and GraphQL (or JSON) API.
  • Experience integrating with third party solutions via web services API.
  • Experience with Atlassian applications including BitBucket, Jira, Confluence, and other 3rd party development tools and utilities.
  • Self-motivated, self-starting, an attention to detail and a great team player.
  • The highest level of personal honesty, integrity and commitment; unquestionably walks the talk so others want to follow.
  • Strong communication skills.

Ideal Candidate will have:

  • Familiarity with enterprise NGS cloud-based systems, ideally Illumina’s BaseSpace / Design Studio
  • Background in biological sciences, DNA applications, either from education or work experience.

Miscellaneous

  • Job located in Paris, France
  • Start date: ASAP 
  • Contact: ftn@dnascript.co
Apply now

The role

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for an accomplished Field Service Engineer to support our partners and customers in their use and application of DNA Script’s commercial product. 

The individual will be responsible for leading complex technical inquiries in the field including troubleshooting and repairs, coordinating customer feedback and interactions, and representing user experiences within the company to aid development of next generation products. 

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.    

The position will be based in Paris.

Responsibilities

  • Installs and optimizes hardware/software/network products and configurations at customer sites.
  • Diagnoses and resolves product performance problems.
  • Performs maintenance and repairs
  • Ensures customer satisfaction by advising customers on preventive maintenance and configurations, which may impact product performance.
  • Proactively responds to potential equipment issues to prevent unplanned interruption of customers’ business.
  • Delivers fully integrated solutions, which may include peripherals, communications, operating systems and applications software.
  • Trains other field engineers and customers in the company’s system products. 
  • Provides user-oriented and service-related  input to ongoing and new development projects.

Experience

  • Bachelors within the science field — e.g. biomedical engineering,  analytical biochemistry, biotechnology or similar is highly preferred
  • 4+ years of experience in a similar position and/or experience as an end-user of analytical instrumentation

Ideal Candidate will have

  • Experience or expertise with Laboratory Automation solutions (eg. pipetting robots, electronics and linear actuators) and systems involving reagents and consumables
  • Experience with troubleshooting and problem solving Customer service and solutions-oriented, with capability to precisely document issues, root cause analyses, troubleshooting experimentation and resolutions/repairs.
  • DNA Synthesis Experience, or Utilization of Synthetic Oligos in a biochemical application.
  • Excellent written and verbal communication skills
  • Ability to travel extensively including overnight travel as dictated by business needs

Miscellaneous

  • Remote Job based in Paris (France). Requires 75% travel to corporate offices and client sites throughout EU countries.
  • Start date: Q3 2020
Apply now

The role

Become part of our Product Development team and help us to design and conduct feasibility studies investigating and optimizing the interactions among reagents, consumables, hardware and protocols.  You will be able to use statistical methods to evaluate data, identify trends and make clear recommendations based on data.  You will interface with a cross-functional project team to ensure alignment with design requirements and that the product meets approved quality standards.  You will maintain detailed documentation throughout all phases of product development, and provide technical input for FMEAs, risk mitigation strategies and designs.

Responsibilities

•             Assay characteristics of reagents and consumables, including both objective and performance criteria

•             Troubleshoot hardware and software protocols and sources of variability derived from both reagents and consumables

•             Formulate test batches of reagents for experimental use and performance characterization.

•             Contribute to formulation of production lots of reagents following defined Work Instructions and completing batch records

•             Perform acceptance tests on production batches of reagents and consumables

•             Preparation of specific reagents and consumables for daily experimentation and performance characterization 

•             Analyze data using analytical tools (e.g., Excel, Python, R, ImageJ), documenting and presenting results to the team

•             Create, track, monitor, and report metrics and key performance indicators for DNA Script instrument systems

•             Perform system and subsystem verification and validation protocols

•             Manage reagent stability study design, and execution.  Investigate alternate materials to enhance reagent stability and/or improve system design/performance

•             Troubleshoot and optimize fluidic dispense systems, thermal control systems and related subsystems.  Develop and document acceptance / verification tests as required.

•             Complete documentation to support testing procedures including data capture, forms, logbooks, and inventory batch records

•             Define and develop performance-oriented feasibility studies for procedure improvements and newly implemented capabilities within the context of prototype development and improvement of finished products

•             Execute and report the results of end-to-end experimental runs, including oligo  design, run setup, observation of runs-in-progress, performance of a variety of molecular QC assays (qPCR, gel electrophoresis, NGS), data analysis and reporting of single data sets or trends across long term studies. 

Experience

•          BS in Biological Sciences or Engineering with 5+ years of experience in the Life Science and laboratory automation domain

•          Strong skills in laboratory and system feasibility experimentation and Verification and Validation execution, Data Analysis, representation, and presentation, reagent formulation and GLP/GMP documentation.   •             Desire and ability to work in a small interdisciplinary team to develop new technologies at a rapid pace

Ideal Candidate will have

•             Experience in regulated Life Science product/medical device development under design controls is preferred

•             Knowledge of liquid handling and laboratory automation, microfluidics, molecular assay and QC techniques, and reagent and platform manufacturing techniques is preferred.

•             Demonstrated problem-solving and troubleshooting skills along with strong verbal and written communications

•             Organized and detail oriented

•             Ability to work in a team environment

Miscellaneous

  • Job located in South San Francisco
  • Start date: Q3 2020
  • Contact: cdm@dnascript.co
Apply now
Research & Development

The role

DNA Script is looking for a dynamic, talented individual to join the Enzyme Production team for an internship in the fermentation area.  The project consists of optimizing the expression yield of a key enzyme used in our enzymatic DNA synthesis technology. The project includes evaluation of multiple strain constructs in different culture formats (plate, flask, small and large bioreactor) and will be supervised by a confirmed PhD in Fermentation.

Qualifications and experience

Essential

  • Last year of engineering/ master’s degree in biotechnology
  • Good knowledge and skills in microbiological and biochemical techniques such as bacterial growth, protein expression, fermentation.
  • Excellent learning, organizational skills
  • Highly motivated candidate with passion for science

Desirable: 

  • Demonstrated experience in strain screening & fermentation will be advantageous.

Miscellaneous

Start date: June-August 2021

Recruitment process

  1. Phone interview with the manager
  2. Day interview at the office with the manager, cofounders, HR and the team
  3. References check
  4. Timing: around 2-3 weeks
Apply now

Biotechnology platform manager/Biotechnology Automation Scientist

The role

DNA Script is looking for a talented individual to take up a key role within the Applications team. He or she will be in charge of developing and managing the Assembly platform dedicated to produce nucleic acid assemblies based on the company’s enzymatic technology to manufacture de novo synthetic nucleic acids and novel assembly techniques. This platform will play a central role for DNA Script by demonstrating the ability of Syntax and EDS technology to provide oligonucleotides that can be used to produce any targeted synthetic gene.

The candidate will be in charge of implementing the full process of synthetic gene/nucleic acid assembly, from the reception of orders, oligonucleotide design, assembly production, sequencing analysis, QC and customer delivery. He or she will implement the specific assembly strategy defined by the R&D Assembly principal scientists in a given project. In addition, the candidate will be responsible of transferring the protocols developed by the R&D Assembly scientists in the Applications team and adapt them to the Assembly platform in a robust automated way.

To perform these tasks, the candidate will need to interact with many different teams, in particular the R&D Assembly scientists in the Applications team that will develop the assembly protocols and define the assembly strategy for a given project, the Bioinformatics team that will provide the oligonucleotide designs and perform analytics, the Synthesis platform that will produce the starting oligonucleotides and the NGS platform that will analyse the assembled sequences. He or she will be assisted by a technician.

We are seeking an individual who is well organized, proactive, detail-orientated, enjoys problem-solving, and is able to work in a multi-disciplinary role.

Responsibilities

  • Develop and manage an automated Assembly Platform: Ensure efficient and reproducible day to day operations, provide high quality results, ensure high equipment uptime, manage team and resources (equipment, reagents, consumables), 
  • Work collaboratively with groups across the company to set up appropriate projects
  • Perform in-depth analysis of experimental data, 
  • Effectively document and report on platform KPI, QC data and processes,
  • Engage in good laboratory/documentation practices, write Standard Operation Protocols (SOPs) and enforce their correct use,
  • Actively contribute towards critical company milestones, with a willingness to work outside immediate area of expertise where required.

Qualifications and experience

Essential

  • Process or biotechnology engineering, PhD or similar,
  • Minimum of five years’ experience in managing a service platform, preferentially in the field of molecular biology, 
  • Experience in molecular biology methods including PCR, restriction digestion, DNA/RNA purification, and nucleic acid characterisation and/ or in nucleic acid synthesis.
  • Experience in automation, liquid handlers, high throughput screening or analysis, 
  • Excellent knowledge of Excel and other Microsoft Tools, 
  • Excellent organisational, analytical, and systematic troubleshooting skills,
  • Excellent communication and interpersonal skills, 
  • Highly motivated, with a passion for developing tools and methods, 
  • Ability to work independently and as part of a large multi-disciplinary team,
  • Dynamic with positive attitude willing to engage at a very high level, 
  • Excellent English language level as well as at least an intermediate French language level.  

Desirable

  • Experience in following or implementing quality systems such as ISO 9001 or ISO 13485.
  • Experience in coding with Visual Basic Script (VBS), python or the like. 
  • Knowledge on gene assembly protocols

Recruitment process

1- Phone interview with manager

2- Day interview with manager, cofonders, HR and the team

3- References check

4- Timing: 2 to 3 weeks

The offer is available here: https://www.welcometothejungle.com/fr/companies/dna-script/jobs/biotechnology-platform-manager_le-kremlin-bicetre

Apply now

La mission 

DNA Script recherche un ingénieur en mécanique afin de participer à la conception (CAO), l’assemblage, les essais et la maintenance des prototypes qui seront nos futurs produits ou pour nos fabrications internes de réactifs. 

Les instruments automatisés utilisés par DNA Script mettent en œuvre les outils habituels de la robotique (motorisations, transmissions, guidages, capteurs, chauffage, électronique simple (arduino) et codage (Python, VB …) ainsi que des fonctions annexes mais essentielles de thermique, de mélange ou de micro-fluidique (dispense précise de liquide de quelques µl, valves, pompes…). 

Vous serez chargé de concevoir, de réparer ou de modifier tous nos automates en recherche et développement en leur ajoutant de nouvelles fonctions thermiques, optiques, fluidiques ou mécaniques et fonctions des demandes des chercheurs. 

Vous évoluerez au sein d’une équipe multidisciplinaire de chercheurs en biologie, d’ingénieurs en intégration système qui travailleront avec vous pour tester et améliorer vos réalisations de façon dynamique, rapide et efficace. Votre activité et vos résultats auront un impact direct au niveau du développement des futurs produits dans l’amélioration des produits actuels et des procédés de fabrication. Bien que très technique la mission demande une bonne compréhension des phénomènes physiques, fluidiques, thermiques, mis en jeu dans les instruments concernés.

Responsabilités 

  • Conception générale (mécanique, électronique, fluidique, thermique) d’instruments automatisés
  • Dimensionnement mécanique et électromécanique de pièces et de systèmes 
  • Réalisation de travaux d’assemblage et d’ajustage mécanique, câblage électrique, programmation simple électronique 
  • Test des assemblages, tests fonctionnels et contrôles des spécifications
  • Suivis des approvisionnements : commandes des pièces, suivi des sous-traitances, gestion des pièces de rechanges 

Expériences et compétences 

Requises 

  • Ecole d’ingénieur spécialité ou mécanique robotique :  ENSMM Besançon, INSA mécanique, SUPMECA, UTC Compiègne, UTT Troyes, IFMA Clermont….
  • 10 ans d’expérience dans la conception et réalisation de système automatisé pour le diagnostic, ou les sciences de la vie, ou machines spéciales 
  • Connaissance et pratique des circuits électroniques pour la commande des robots
  • Bon communiquant, compréhension des demandes non techniques et traduction en système
  • Travail d’équipe, bonne réactivité, débrouillard et créatif

Souhaitables 

  • Anglais courant 

Informations diverses 

  • Poste basé au Kremlin-Bicêtre (Paris)
  • Contrat : CDI
  • Début : ASAP

Apply now

The role

DNA Script is looking for a dynamic, talented individual to join the Enzyme Engineering team for an internship in developing high throughput selection strategies for protein engineering.  The project consists of characterizing and enhancing the performance of accessory enzymes in our enzymatic DNA synthesis technology to deliver ready to use, high quality oligonucleotides. The project includes aspects of enzymatic characterization, buffer optimization and enzyme engineering and will be supervised by a confirmed PhD in Molecular Microbiology.

Qualifications and experience

Essential

  • Last year of engineering/ master’s degree in molecular (micro)biology or biochemistry.
  • Good knowledge and skills in microbiological, molecular and biochemical techniques such as bacterial growth and transformation, PCR-based technologies, cloning and mutant construction, DNA analytical methods, Illumina and Sanger sequencing and enzymatic assays.
  • Ability to work as part of a large multi-disciplinary team
  • Good level of English 
  • Excellent learning, organizational skills
  • Highly motivated candidate with passion for science

Desirable: 

  • Demonstrated experience in biochemical and molecular biology techniques will be advantageous.

Miscellaneous

Start date: 01 June 2021

Recruitment process

  1. Phone interview with the manager
  2. Day interview at the office with the manager, cofounders, HR and the team
  3. References check
  4. Timing: around 2-3 weeks
Apply now

Le rôle

Le technicien de laboratoire travaillera dans l’équipe de production de nucléotides pour aider à la production interne de nucléotides, l’un des réactifs clés de la technologie de DNA Script. Sous supervision générale et suivant des instructions de travail écrites, votre tâche sera de synthétiser et de purifier les nucléosides / nucléotides et leurs dérivés, ainsi que d’effectuer d’autres tâches de laboratoire assignées. Vous effectuerez des analyses de qualité et des purifications en utilisant la chromatographie liquide haute performance (HPLC) ainsi que la chromatographie flash (FC) tout en conservant une documentation détaillée de tous les processus de travail.

Responsibilités

  • Production de nucléosides / nucléotides selon les instructions de travail (WI) et dossier de fabrication par lots (BMR)
  • Maintenir une documentation détaillée de tous les processus de travail
  • Effectuer d’autres tâches de laboratoire assignées par le chef d’équipe
  • Participer à une réunion de l’équipe de chimie et présenter un rapport technique
  • Maintenir les pratiques de sécurité du laboratoire

Experiences et Compétences

Indispensable

● Détient un diplôme dans le domaine de la chimie ou du génie chimique
●Connaissance des techniques de chimie organique synthétique, y compris, mais sans s’y limiter, les compétences de laboratoire, l’interprétation des données de diverses techniques spectroscopiques
●Expérience dans diverses méthodes d’analyse et de purification : chromatographie sur couche mince, chromatographie flash sur colonne flash, HPLC
● Solides compétences en tenue de registres
● Capacité à travailler de manière autonome et en équipe
● Maîtrise de l’anglais (parler, lire et rédiger des rapports)  

Souhaitable:

● Expérience en synthèse à grande échelle de composés organiques

● Expérience dans le système ERP, EBR (Electronic Batch Record) et QMS

Divers

  • Emploi situé au Kremlin-Bicêtre (région parisienne)
  • Date de début: ASAP
  • Contact: wwu@dnascript.co

Apply now

Mission

DNA Script is looking for a R&D DSP Team Leader to strengthen the development and the production of its proprietary enzymes. You will join the enzyme production team composed of 8 scientists and be in charge of the purification activity under the supervision of the enzyme production group leader. You will be in charge of optimizing the purification process of different enzymes at different scale in order to increase the purification yield of those enzymes. You will have to collaborate with other teams, especially enzyme engineering team, to develop and improve DNA Script technology.

Responsibilities

  • Supervise DSP team composed of three members
  • Manage operational activities of purification area (production and optimization)
  • Identify and implement new downstream technology/instrumentation for continuous improvement of yield and throughput
  • Develop robust downstream process and support process transfer to external partners
  • Define strategy for the development, scale-up and optimization of the DSP process for multiple enzymes
  • Conduct experiments, interpreting results, drawing conclusions and recommending options for future experiments to achieve project goals
  • Support generation of WIs, SOPs, batch records and reports for internal tracking, technology transfer and development processes.
  • Recognize and resolve technical problems and evaluate options for complex experimental problems
  • Participate in routine maintenance and lab safety by following laboratory procedures and GLP

Qualifications and experiences

  • Hold a Master/Engineer degree or PhD preferably in biochemistry, protein purification, biotechnology or related fields
  • 8+ years of experience in proteins purification
  • Extensive theoretical knowledge and hands-on experience with chromatography techniques
  • Industrial experience in purification scale-up at pilot/commercial scale
  • Demonstrated management and leadership skills of scientific team
  • Demonstrated experience with managing multiple development projects in parallel
  • Excellent oral and written communication skills in English, good level of French is a plus
  • Proactive with excellent team spirit
  • Appreciate lab work in a dynamic and evolving environment

Miscellaneous

  • Job located in Kremlin-Bicêtre (Paris area, 5 minutes from Porte d’Italie)
  • Start Date: as soon as possible
  • Contact: send your resume to jl@dnascript.com
Apply now

The role

DNA Script is looking for a talented chemist/biochemist to strengthen its Analytics platform which is an important part of the Development team. The role will be at the crossroad of surface chemistry and analytics providing the team with a novel vision and understanding of their process.

The candidate will be mainly in charge of:

  • Developing analytical methods to characterize modified oligonucleotides produced by enzymatic DNA synthesis
  • Study solid supports used for DNA synthesis and their role at different stages of the synthesis process by optical/confocal microscopy

We are looking for a person who is rigorous, methodical, well organized, detail-oriented, problem-solver and capable of playing a cross-functional role within a multidisciplinary team.

Responsibilities

  • Develop optical methods for the characterization of fluorescent/non-fluorescent oligonucleotides, including PCR/qPCR probes
  • Implement confocal microscopy as new characterization tool for solid supports used for DNA synthesis
  • Perform routine analysis of modified DNA and solid supports
  • Design and conduct experiments to support R&D projects
  • Help enrich analytical platform with instruments suitable for our R&D departments
  • Write analytical protocols and analytical development reports
  • Participate in the scientific and technical state of the art review

Qualifications and experience

Essential

  • Master 2 or Engineer in Chemistry/Biochemistry or any related field
  • Hands-on experience with optical characterization of biomolecules (UV-Vis, fluorescence, FRET, …)
  • At least 3 to 5 years of hands-on experience with optical microscopy / confocal microscopy
  • Ability to design, execute, interpret, and troubleshoot experiments
  • Excellent verbal and written communication, strong organizational and interpersonal skills
  • Highly motivated, passionate about developing tools and methods
  • Ability to work independently and within a large multidisciplinary team
  • Excellent level of English and good level of French

 Desirable

  • First significant experience in laboratory and biotechnology environment
  • Experience with fluorescent DNA probes (qPCR/TaqMan)
  • Familiar with image analysis software (ImageJ, …)

Miscellaneous

  • Job located in Kremlin-Bicêtre (Paris area)
  • Start date: ASAP

Apply now