Transforming how molecular biology
translates to human health, personalized
medicine and synthetic biology.

our history
DNA Script believes in engineering biology to accelerate breakthroughs in life science and human health.
DNA Script was created to revolutionize DNA write with enzymes. Our core R&D efforts have produced innovations in enzyme engineering, surface and nucleotide chemistries, and instrumentation.  The integration of these innovations has resulted in SYNTAXTM, the world’s first benchtop DNA printer powered by enzymatic technology. With continued advancement and innovation, we believe DNA Script’s enzymatic DNA synthesis technology is poised to become the engine of genomics research as well as personalized medicine. 
our team

We’re science-driven thinkers, makers, dreamers and do-ers.

Founders
Thomas Ybert, PhD Co-Founder and CEO
Sylvain Gariel Co-Founder and COO
Xavier Godron Co-Founder and CTO
Meet the DNA Script team
See full team directory
Board Members
Thomas Ybert, PhD Co-Founder and CEO
Sylvain Gariel Co-Founder and COO
Joachim Rothe LSP
Nick Naclerio Illumina Ventures
Josko Bobanovic Sofinnova Partners
Philippe Peltier Kurma Partners
Paul MacEwan Independent Board Member
Heiner Dreismann Independent Board Member
Laurent Higueret Board Observer
Joey Mason Board Observer
our partners
lspvc-logo
illumina-ventures
sofinnova-logo
bpi-france-logo
m-ventures
kurma-partners-logo
idinvest-logo
easme-logo
institut-pasteur-logo
la-french-tech-logo
agoranov-logo
Casdin Capital Logo – Transparent – Large
Danaher
Agilent
values
We’re looking for great individuals who are committed to our company values.

Excellence

Take responsibility for your work. Aim to act, do and behave with the goal of reaching the unreachable.


Transparency

Give sincere, reliable and trustworthy information. Bring objective facts, no matter how they look.


Benevolence

Create a positive environment for everyone. Be supportive to the team, the company and your colleagues.

careers
We are synthesizing a technology revolution. Join us.
General & Administration

Mission

Nous recherchons un(e) contrôleur de gestion afin de renforcer l’équipe Corporate (Administratif, Finance, Comptabilité et RH) de DNA Script. Vous travaillerez en étroite collaboration avec le Finance Manager et l’équipe de management sur tous les aspects financiers de la société et de sa filiale aux US.

Responsabilités

  • Participer à l’élaboration du budget annuel avec le Finance Manager
  • Assurer le suivi mensuel du budget pour chacune des équipes de DNA Script et les accompagner pour respecter celui-ci
  • Participer à la mise en place du process de Ventes et au lancement commercial de SYNTAX, la première imprimant à ADN commercialisé par DNA Script en 2021
  • Superviser le suivi des comptes Clients
  • Superviser les clôtures mensuelles, trimestrielles et annuelles des comptes en collaboration avec notre comptable et notre assistante administrative pour la société mère française et la filiale aux US
  • Superviser la consolidation des comptes
  • Réaliser les analyses de performance de l’entreprises en lien avec la clôture des comptes (analyse des sales,des opex et des écarts au budget)
  • Contribuer à la production des documents utilisés dans le cadre de nos Boards d’investisseurs
  • Supeviser le suivi de la Trésorerie (analyse des projections produites par notre comptable et validation des paiements)
  • Être un interlocuteur privilégié pour nos auditeurs et experts comptables en France et aux US
  • Contribuer à l’amélioration de notre contrôle interne par le design, la rédaction et la mise en place de nouveaux process
  • Prendre une part active dans le déploiement de notre ERP

Qualifications et expérience

  • Diplôme d’Ecole de Commerce ou Master en Finance d’Entreprise
  • 2 ans minimum d’expérience professionnelle
  • Expérience en cabinet d’audit appréciée
  • Maîtrise des logiciels informatiques de bureautique (Word, Excel, Power Point) et de traitement comptable et fiscal
  • Bonne connaissance des normes comptables françaises et internationales (IAS/IFRS/US GAAP)
  • Bonne connaissance des normes juridiques (droit des sociétés, du travail et social), fiscales et comptables
  • Anglais courant (équipe internationale)
  • Connaissance de NetSuite / Oracle est un plus
  • Bonne gestion du stress 
  • Grande rigueur, souci du détail et du respect des délais
  • Excellente qualité d’organisation et d’adaptation au changement
  • Capacité à être polyvalent
  • Aptitude à travailler en autonomie et en transverse sur des sujets variés
  • Excellente communication écrite et verbale
  • Appétence pour les sciences de la vie

Informations diverses

  • Poste basé au Kremlin-Bicêtre (94) – Ile de France – sortie métro ligne 7
  • Date d’embauche : dès que possible
  • Contrat : CDI à plein temps
  • Rémunération : à définir selon expérience
  • Contact : tle@dnascript.co et hiring@dnascript.co
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionately impatient people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write.” We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our DNA On Demand platform not only has the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.    

The Role

We are looking for an experienced Marketing Communications Manager who can be our messaging “conductor” and develop communications from ground zero. You will own the development of the strategic messaging and direct the tactical integration of our brand and product messaging in communications across all media necessary to achieve our sales objectives. You will drive the communications roadmap, with a strong focus on digital marketing, that maximizes the reach of our products & services and delivers on our growth expectations. This is a mission critical role on the Commercial team that requires collaboration with team members in Marketing, Sales, Product Development and senior management. We’re looking for the leader who can bring together the essential elements of our brand in all of our product focused and corporate communications.  You will be the visionary, drive the tempo and harmonize our communications to deliver success.

Responsibilities

  • Direct and execute corporate and product marketing communications acting as brand champion; own messaging across all media channels.
  • Own corporate and product messaging, gain buy-in across leadership, and deploy consistently across channels. Periodically review and modify to address applicable market audiences.
  • Lead and develop go-to-market plans for new product introductions by ensuring consistent      messaging and positioning, and coordinate execution across communication media channels and      sales training     .
  • Drive & execute product marketing programs and campaigns to accelerate adoption of our platforms through strong partnerships with product management, applications, and sales.
  • Develop, budget, monitor, and evaluate the success of campaigns for optimization and continued effectiveness; determine ROI.
  • Formulate and drive digital strategy and content roadmap to transform and maximize reach, from ideation through execution and implementation.
  • Proactively identify, execute, and refresh content strategies to generate awareness, demand, and improved customer experience and conversion.
  • Own and manage digital marketing assets; build a collateral portfolio for digital, virtual & print interactions.
  • Collaborate with Product Management and Applications to develop and produce awareness & education materials for market outreach & expansion.
  • Direct and manage consultants, freelancers, agencies in multiple countries.
  • Develop product packaging in line with brand.
  • Direct PR/IR programs to establish company as leader to attract investors, customers, and employees.
  • Own marketing campaign management and data capture within the CRM system.

Requirements

  • Have a passion for commercializing platforms that are game-changing and require an audience behavioral shift
  • Proven experience in building communications and assets across marketing channels/media from ground zero
  • Experienced with investor communications; IPO experience a plus
  • Experienced in global product launches or specific programs and campaigns to support corporate & commercial strategy
  • Have the drive and initiative to learn new skills and can demonstrate complete ownership of assigned marketing campaigns and programs
  • Creative thinker and can help establish new frontiers in how we communicate with prospects, customers, investors, be unafraid to re-draw the box, etc.
  • Ability to convert complex technical concepts and product capabilities into crisp messages on benefits for the target audience
  • Effectiveness in building relationships with key stakeholders necessary for collaboration at all levels and influence without authority. Gain alignment and achieve results by power of influence alone
  • BA/BS degree in marketing or equivalent, preferably with background in Biological Sciences
  • 10+ years of marketing experience in a similar position within the life science industry.
  • Strong writing & graphic design appreciation skills are required for this role; must demonstrate proven experience in writing digital content, technical writing, and copywriting as well as knowing when the right picture or graphic will speak more effectively. .
  • Excellent communication skills with ability to present technical presentation in sales trainings, small groups and customers.
  • Ability to travel up to 25% domestic and international.

Preferably

  • Start-up mind-set and experience  is strongly preferred.
  • Experienced across the marketing continuum
  • Understanding of the new product introduction and product lifecycle management processes
  • Account, vendor, or project management experience

Miscellaneous

  • Job location: South San Francisco, US or Paris, France
  • Requires travel among DNA Script corporate offices and client sites throughout US and Europe.
  • Start date: Q1 2021

Contact: hiring@dnascript.co

Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionately impatient people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write.” We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our DNA On Demand platform not only has the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.    

The Role

We are looking for an experienced Marketing Communications Manager who can be our messaging “conductor” and develop communications from ground zero. You will own the development of the strategic messaging and direct the tactical integration of our brand and product messaging in communications across all media necessary to achieve our sales objectives. You will drive the communications roadmap, with a strong focus on digital marketing, that maximizes the reach of our products & services and delivers on our growth expectations. This is a mission critical role on the Commercial team that requires collaboration with team members in Marketing, Sales, Product Development and senior management. We’re looking for the leader who can bring together the essential elements of our brand in all of our product focused and corporate communications.  You will be the visionary, drive the tempo and harmonize our communications to deliver success.

Responsibilities

  • Direct and execute corporate and product marketing communications acting as brand champion; own messaging across all media channels.
  • Own corporate and product messaging, gain buy-in across leadership, and deploy consistently across channels. Periodically review and modify to address applicable market audiences.
  • Lead and develop go-to-market plans for new product introductions by ensuring consistent      messaging and positioning, and coordinate execution across communication media channels and      sales training     .
  • Drive & execute product marketing programs and campaigns to accelerate adoption of our platforms through strong partnerships with product management, applications, and sales.
  • Develop, budget, monitor, and evaluate the success of campaigns for optimization and continued effectiveness; determine ROI.
  • Formulate and drive digital strategy and content roadmap to transform and maximize reach, from ideation through execution and implementation.
  • Proactively identify, execute, and refresh content strategies to generate awareness, demand, and improved customer experience and conversion.
  • Own and manage digital marketing assets; build a collateral portfolio for digital, virtual & print interactions.
  • Collaborate with Product Management and Applications to develop and produce awareness & education materials for market outreach & expansion.
  • Direct and manage consultants, freelancers, agencies in multiple countries.
  • Develop product packaging in line with brand.
  • Direct PR/IR programs to establish company as leader to attract investors, customers, and employees.
  • Own marketing campaign management and data capture within the CRM system.

Requirements

  • Have a passion for commercializing platforms that are game-changing and require an audience behavioral shift
  • Proven experience in building communications and assets across marketing channels/media from ground zero
  • Experienced with investor communications; IPO experience a plus
  • Experienced in global product launches or specific programs and campaigns to support corporate & commercial strategy
  • Have the drive and initiative to learn new skills and can demonstrate complete ownership of assigned marketing campaigns and programs
  • Creative thinker and can help establish new frontiers in how we communicate with prospects, customers, investors, be unafraid to re-draw the box, etc.
  • Ability to convert complex technical concepts and product capabilities into crisp messages on benefits for the target audience
  • Effectiveness in building relationships with key stakeholders necessary for collaboration at all levels and influence without authority. Gain alignment and achieve results by power of influence alone
  • BA/BS degree in marketing or equivalent, preferably with background in Biological Sciences
  • 10+ years of marketing experience in a similar position within the life science industry.
  • Strong writing & graphic design appreciation skills are required for this role; must demonstrate proven experience in writing digital content, technical writing, and copywriting as well as knowing when the right picture or graphic will speak more effectively. .
  • Excellent communication skills with ability to present technical presentation in sales trainings, small groups and customers.
  • Ability to travel up to 25% domestic and international.

Preferably

  • Start-up mind-set and experience  is strongly preferred.
  • Experienced across the marketing continuum
  • Understanding of the new product introduction and product lifecycle management processes
  • Account, vendor, or project management experience

Miscellaneous

  • Job location: South San Francisco, US or Paris, France
  • Requires travel among DNA Script corporate offices and client sites throughout US and Europe.
  • Start date: Q1 2021

Contact: hiring@dnascript.co

Apply now

The role

DNA Script is looking for a talented patent attorney to join the legal department, in a role that is central and critical to support the development of the company.  The candidate will be responsible for (i) patent preparation and prosecution ; (ii) patent committee and idea sourcing ; and (iii) related and competitor IP monitoring. writing and filling patent applications, managing existing patent portfolio and track office actions, animating patent committee and monitoring new ideas and findings, monitoring competitive landscape and IP.

Responsibilities

  • Drafting and filling patent applications
  • Managing existing patent and applications portfolio, maintaining internal docket and track office actions
  • Overseeing IP advisors and outside patent attorneys involved in patent prosecution
  • Managing inventorship and ensuring proof of ownership of the company invention via assignments
  • leading and organizing patent committees and new invention related processes
  • Monitoring new ideas and finding generated by the organization
  • Organizing and lead the interaction with innovating stakeholders in the Company to gather new ideas and findings
  • Track and follow operational team work related to patent filling and prosecution
  • Monitoring competitive landscape and IP
  • Conduct freedom-to-operate studies on regular basis or on ad-hoc requests
  • Conduct IP landscape analysis as requested by management or operational activities
  • Sensitize and train operational teams on importance and processes of IP
  • Manage internal communication on IP related activities
  • Provide legal help/support with general agreements and contract upon requests

Qualifications and experience

Essential

  • Has a Juris Doctorate or equivalent
  • Has an advanced degree in Molecular Biology, Bioengineering, Molecular Genetics, Synthetic Biology, Microbiology,  or a related biotechnology-relevant discipline or an advanced degree in Organic Chemistry, Nucleic Acid Chemistry or related biochemistry-relevant discipline.
  • Cumulate 3-5 years of total prior legal experience including time at a top-tier law firm and/or pharmaceutical or biotechnology industries
  • Proven track record in drafting and prosecuting biotechnology-related patent applications
  • Experience in working with research and development teams and environment
  • Experience in managing, organizing or taking part in IP committee or relevant processes
  • Possess working knowledge of transactional, commercial, and intellectual property law
  • Can handle large volume of work on a prioritized basis
  • Has exceptional attention for detail and accuracy abilities. As well as the ability to set a course that is optimal for the company in the context of both ambiguity and complicated and conflicting priorities.
  • Strong interactive skills and collaborative attitude to work effectively in a team environment
  • Has excellent organizational, project management and problem-solving skills with the ability to ensure to stay in budget and time while communicating clearly to the rest of the management team.
  • Has the highest levels of personal honesty, integrity and commitment.

Desirable

  • Experience in the field of DNA such as DNA synthesis or DNA sequencing
  • Start-up/small company experience
  • International and preferably US experience or work for a US firm

Miscellaneous

  • Job located in Kremlin-Bicêtre (Paris area)
  • Start date: ASAP

Contact

vb@dnascript.co ; ty@dnascript.co

Apply now
Manufacturing Operations

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a Manufacturing & Procurement Technician who will be primarily responsible for the preparation of kits under good laboratory practices. This role will include inventory follow up, execute products preparation to build the kits with full traceability and interact with R&D teams to support customer demands. In addition, she/he will be responsible for procurement of all necessary items for kits production.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.     The position will be US based, in the South San Francisco, California office.

Responsibilities

  • Prepare buffers, solutions, and other kit components following approved protocols, including the use and safe handling of hazardous chemicals, data input and record keeping
  • Use approved analysis techniques to characterize and ensure quality of synthesis reagents and products
  • Work with supply chain and logistics to optimize packaging and shipments, eliminating back orders
  • Maintain inventory for laboratory and manufacturing operations @ SSF site
  • Maintain finished goods inventory, work in process and raw materials; recommend material orders as needed to maintain stocks for production
  • Monitor, qualify,  and maintain calibration of laboratory instrumentation used for manufacturing
  • Participate in planning activities pertaining to kit production
  • Perform / assist with daily oligosynthesis operations and provide feedback to development
  • Perform reagent manufacturing, logistics planning and other tasks as necessary in a laboratory environment
  • Assist in assembly and packaging of reagents and consumables for both domestic and international shipment
  • Procure and receive materials to support kit production and shipping
  • Execute tasks under approved SOPs, document production using batch records and contribute to improving overall quality in operations
  • Contribute to development and execution of incoming inspection of received goods and stability tests
  • Work under the supervision of Manufacturing Operations management

Experience

  • Bachelors degree in Biology, Biochemistry, Chemistry or related field.
  • 1-3 years of relevant experience is preferred
  • Experience working in laboratory
  • Experience working under GLP (Good Laboratory Practices) and following good documentation and compliance practices
  • Experience with laboratory safety procedures and documentation
  • Detail oriented and meticulous attention to detail
  • Willingness to take/accept new responsibilities and able to work with minimal supervision.
  • Demonstrated ability to work in multidisciplinary teams

Miscellaneous

  • Job located in South San Francisco
  • Start date: Q1 2021

Contact: cma@dnascript.co

Apply now
Product Development

The role

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for an accomplished Field Service Engineer to support our partners and customers in their use and application of DNA Script’s commercial product. 

The individual will be responsible for leading complex technical inquiries in the field including troubleshooting and repairs, coordinating customer feedback and interactions, and representing user experiences within the company to aid development of next generation products. 

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.    

The position will be based in Paris.

Responsibilities

  • Installs and optimizes hardware/software/network products and configurations at customer sites.
  • Diagnoses and resolves product performance problems.
  • Performs maintenance and repairs
  • Ensures customer satisfaction by advising customers on preventive maintenance and configurations, which may impact product performance.
  • Proactively responds to potential equipment issues to prevent unplanned interruption of customers’ business.
  • Delivers fully integrated solutions, which may include peripherals, communications, operating systems and applications software.
  • Trains other field engineers and customers in the company’s system products. 
  • Provides user-oriented and service-related  input to ongoing and new development projects.

Experience

  • Bachelors within the science field — e.g. biomedical engineering,  analytical biochemistry, biotechnology or similar is highly preferred
  • 4+ years of experience in a similar position and/or experience as an end-user of analytical instrumentation

Ideal Candidate will have

  • Experience or expertise with Laboratory Automation solutions (eg. pipetting robots, electronics and linear actuators) and systems involving reagents and consumables
  • Experience with troubleshooting and problem solving Customer service and solutions-oriented, with capability to precisely document issues, root cause analyses, troubleshooting experimentation and resolutions/repairs.
  • DNA Synthesis Experience, or Utilization of Synthetic Oligos in a biochemical application.
  • Excellent written and verbal communication skills
  • Ability to travel extensively including overnight travel as dictated by business needs

Miscellaneous

  • Remote Job based in Paris (France). Requires 75% travel to corporate offices and client sites throughout EU countries.
  • Start date: Q3 2020
Apply now

The role

Become part of our Product Development team and help us to design and conduct feasibility studies investigating and optimizing the interactions among reagents, consumables, hardware and protocols.  You will be able to use statistical methods to evaluate data, identify trends and make clear recommendations based on data.  You will interface with a cross-functional project team to ensure alignment with design requirements and that the product meets approved quality standards.  You will maintain detailed documentation throughout all phases of product development, and provide technical input for FMEAs, risk mitigation strategies and designs.

Responsibilities

•             Assay characteristics of reagents and consumables, including both objective and performance criteria

•             Troubleshoot hardware and software protocols and sources of variability derived from both reagents and consumables

•             Formulate test batches of reagents for experimental use and performance characterization.

•             Contribute to formulation of production lots of reagents following defined Work Instructions and completing batch records

•             Perform acceptance tests on production batches of reagents and consumables

•             Preparation of specific reagents and consumables for daily experimentation and performance characterization 

•             Analyze data using analytical tools (e.g., Excel, Python, R, ImageJ), documenting and presenting results to the team

•             Create, track, monitor, and report metrics and key performance indicators for DNA Script instrument systems

•             Perform system and subsystem verification and validation protocols

•             Manage reagent stability study design, and execution.  Investigate alternate materials to enhance reagent stability and/or improve system design/performance

•             Troubleshoot and optimize fluidic dispense systems, thermal control systems and related subsystems.  Develop and document acceptance / verification tests as required.

•             Complete documentation to support testing procedures including data capture, forms, logbooks, and inventory batch records

•             Define and develop performance-oriented feasibility studies for procedure improvements and newly implemented capabilities within the context of prototype development and improvement of finished products

•             Execute and report the results of end-to-end experimental runs, including oligo  design, run setup, observation of runs-in-progress, performance of a variety of molecular QC assays (qPCR, gel electrophoresis, NGS), data analysis and reporting of single data sets or trends across long term studies. 

Experience

•          BS in Biological Sciences or Engineering with 5+ years of experience in the Life Science and laboratory automation domain

•          Strong skills in laboratory and system feasibility experimentation and Verification and Validation execution, Data Analysis, representation, and presentation, reagent formulation and GLP/GMP documentation.   •             Desire and ability to work in a small interdisciplinary team to develop new technologies at a rapid pace

Ideal Candidate will have

•             Experience in regulated Life Science product/medical device development under design controls is preferred

•             Knowledge of liquid handling and laboratory automation, microfluidics, molecular assay and QC techniques, and reagent and platform manufacturing techniques is preferred.

•             Demonstrated problem-solving and troubleshooting skills along with strong verbal and written communications

•             Organized and detail oriented

•             Ability to work in a team environment

Miscellaneous

  • Job located in South San Francisco
  • Start date: Q3 2020
  • Contact: cdm@dnascript.co
Apply now
Research & Development

The Role

DNA Script is looking for a dynamic, talented individual to join the Company for an internship in image acquisition and image analysis of inkjet-printed droplets containing enzymes.

The intern will help improve a prototype printer for the synthesis of DNA microarrays by automating the image acquisition process. Currently, each cycle in the DNA synthesis process involves the printing of up to one million picolitre droplets followed by imaging and wet processing of the microarray substrate.

The aim of the internship will be to determine the individual positions and sizes of the droplets in under 3 minutes and identify missing, non-spherical and out-of-position droplets. Real-time reporting will allow corrective actions to be taken and post-synthesis quality metrics will enable DNA Script to determine whether any increase in product purity is due to improved print quality and/or process improvements such as more vigorous washing of the slide or a new ink formulation. If time allows, the intern will also help automate the whole synthesis cycle by linking together different pieces of software. 

The intern will receive an introduction to DNA Script and the prototype printer before conducting a short literature review and sourcing and installing any software and hardware deemed necessary to achieve the stated aims. He / she will be supervised by two PhD-qualified scientists with experience in optics and will interact with other members of DNA Script’s multidisciplinary team as needed.

Qualifications and experience

Essential

  • Last year of engineering school in the field of chemistry/biochemistry
  • Knowledge of image manipulation software such as Fiji (/ImageJ) and Gimp
  • Experience of programming tools and languages such as LabView, C/C++/C# is sought
  • Ability to work as part of a large multi-disciplinary team
  • Excellent learning, organizational skills
  • Highly motivated candidate with passion for science

Desirable

  • Hardware and optical imaging knowledge would be valuable though is not essential.
  • Good level in French and/or English

Miscellaneous

  • Job located in Kremlin-Bicêtre (Paris area)
  • Start date: As soon as possible
  • Compensation: 1200€ / month

Apply now

The role

DNA Script is looking for a highly motivated, well organized team-player to join the Enzyme Engineering team as a Technician. Your role will be to help us evolve proprietary enzyme variants within an exciting, high-profile oligonucleotide synthesis project.

Responsibilities

•             Express and purify enzyme variants in various scales from 96well plate to 1 L

•             Screening of mutagenesis libraries applying multiple assays

•             Isolate plasmid DNA and determine mutant sequences

•             Participate to the characterization of optimized variants

•             Prepare buffer and reagent stocks needed for the project and perform QC tests prior to usage when needed

•             Keep very good record of experimental data

•             Engagement in good laboratory practices

•             Support the team when needed

Qualifications and experience

Essential

•             Bachelors’ Degree in Biology, Biochemistry or Chemistry

•             ‘Hand on’ working experience in molecular biology or biochemistry lab

•             Familiarity with protein handling and purification

•             Familiarity with DNA handling and purification

•             Familiarity with protein structure and sequence analysis

•             Strong record keeping skills

•             Strong interpersonal skills

•             Good command of the English language

Desirable

•             Experience in directed evolution of proteins

•             Experience in working with liquid-handling robot

Miscellaneous

•             Job located in Kremlin-Bicêtre (Paris area)

•             Start date: ASAP

Contact : th@dnascript.co

Apply now

The role

DNA Script is looking for a talented chemist/biochemist to strengthen its Analytics platform which is an important part of the Development team. The role will be at the crossroad of surface chemistry and analytics providing the team with a novel vision and understanding of their process.

The candidate will be mainly in charge of:

  • Developing analytical methods to characterize modified oligonucleotides produced by enzymatic DNA synthesis
  • Study solid supports used for DNA synthesis and their role at different stages of the synthesis process by optical/confocal microscopy

We are looking for a person who is rigorous, methodical, well organized, detail-oriented, problem-solver and capable of playing a cross-functional role within a multidisciplinary team.

Responsibilities

  • Develop optical methods for the characterization of fluorescent/non-fluorescent oligonucleotides, including PCR/qPCR probes
  • Implement confocal microscopy as new characterization tool for solid supports used for DNA synthesis
  • Perform routine analysis of modified DNA and solid supports
  • Design and conduct experiments to support R&D projects
  • Help enrich analytical platform with instruments suitable for our R&D departments
  • Write analytical protocols and analytical development reports
  • Participate in the scientific and technical state of the art review

Qualifications and experience

Essential

  • Master 2 or Engineer in Chemistry/Biochemistry or any related field
  • Hands-on experience with optical characterization of biomolecules (UV-Vis, fluorescence, FRET, …)
  • At least 3 to 5 years of hands-on experience with optical microscopy / confocal microscopy
  • Ability to design, execute, interpret, and troubleshoot experiments
  • Excellent verbal and written communication, strong organizational and interpersonal skills
  • Highly motivated, passionate about developing tools and methods
  • Ability to work independently and within a large multidisciplinary team
  • Excellent level of English and good level of French

 Desirable

  • First significant experience in laboratory and biotechnology environment
  • Experience with fluorescent DNA probes (qPCR/TaqMan)
  • Familiar with image analysis software (ImageJ, …)

Miscellaneous

  • Job located in Kremlin-Bicêtre (Paris area)
  • Start date: ASAP

Apply now